Function and Biology Details
Reaction catalysed:
L-glutamate = 4-aminobutanoate + CO(2)
Biochemical function:
- not assigned
Biological process:
Cellular component:
Sequence domains:
- Immunoglobulin C1-set
- MHC class II, beta chain, N-terminal
- Immunoglobulin/major histocompatibility complex, conserved site
- Immunoglobulin-like domain
- Immunoglobulin-like domain superfamily
- Immunoglobulin-like fold
- MHC classes I/II-like antigen recognition protein
- MHC class II, alpha chain, N-terminal
1 more domain
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137523 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
H-2 class II histocompatibility antigen, A-D alpha chain
Molecule details ›
Chain: A
Length: 190 amino acids
Theoretical weight: 21.62 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Sequence domains:
Structure domains:
Length: 190 amino acids
Theoretical weight: 21.62 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical:
P04228 (Residues: 24-205; Coverage: 78%)
Sequence domains:
Structure domains:
Glutamate decarboxylase 2; Ig-like domain-containing protein
Molecule details ›
Chain: B
Length: 221 amino acids
Theoretical weight: 25.56 KDa
Source organisms: Expression system: Not provided
UniProt:
Sequence domains:
Structure domains:
Length: 221 amino acids
Theoretical weight: 25.56 KDa
Source organisms: Expression system: Not provided
UniProt:
- Canonical: Q05329 (Residues: 207-230, 233-236; Coverage: 3%)
- Canonical: Q31135 (Residues: 24-25, 30-214; Coverage: 78%)
Sequence domains:
Structure domains:
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
SSRL BEAMLINE BL7-1
Spacegroup:
C2221
Expression system: Not provided
