› 1f2q

X-ray diffraction
2.4Å resolution

CRYSTAL STRUCTURE OF THE HUMAN HIGH-AFFINITY IGE RECEPTOR

Released:
DOI: 10.2210/pdb1f2q/pdb
PDB entry 1f2q coloured by chain, front view.
PDB entry 1f2q coloured by chain, side view.
PDB entry 1f2q coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Crystal structure of the human high-affinity IgE receptor.
Garman SC, Kinet JP, Jardetzky TS
Cell 95 951-61 (1998)
PMID: 9875849

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-536814 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
High affinity immunoglobulin epsilon receptor subunit alpha Chain: A
Molecule details ›
Chain: A
Length: 176 amino acids
Theoretical weight: 20.46 KDa
Source organism: Homo sapiens
Expression system: Trichoplusia ni
UniProt:
  • Canonical: P12319 (Residues: 26-201; Coverage: 76%)
Gene names: FCE1A, FCER1A
Sequence domains:
Structure domains: Immunoglobulins

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL7-1
Spacegroup: C2
Unit cell:
a: 88.59Å b: 69.64Å c: 49.36Å
α: 90° β: 116.69° γ: 90°
R-values:
R R work R free
0.226 0.226 0.254
Expression system: Trichoplusia ni

Quick links

Citations

32 review citations

Fcgamma receptors as regulators of immune responses.
Nimmerjahn et al. (2008)
31 more

8 mentions without citation

Pentraxins and Fc receptors.
Lu et al. (2012)
7 more