› 1fht

Solution NMR

RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES

Released:
DOI: 10.2210/pdb1fht/pdb
PDB entry 1fht coloured by chain, ensemble of 43 models, front view.
PDB entry 1fht coloured by chain, ensemble of 43 models, side view.
PDB entry 1fht coloured by chain, ensemble of 43 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding.
Avis JM, Allain FH, Howe PW, Varani G, Nagai K, Neuhaus D
J Mol Biol 257 398-411 (1996)
PMID: 8609632

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-530970 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
U1 small nuclear ribonucleoprotein A Chain: A
Molecule details ›
Chain: A
Length: 116 amino acids
Theoretical weight: 13.57 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P09012 (Residues: 2-117; Coverage: 41%)
Gene name: SNRPA
Sequence domains: RNA recognition motif
Structure domains: Alpha-Beta Plaits

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Escherichia coli

Quick links

Citations

20 review citations

The RNA recognition motif, a plastic RNA-binding platform to regulate post-transcriptional gene expression.
Maris et al. (2005)
19 more

17 mentions without citation

Characterization of the fast dynamics of protein amino acid side chains using NMR relaxation in solution.
Igumenova et al. (2006)
16 more