› 1hhv

Solution NMR

SOLUTION STRUCTURE OF VIRUS CHEMOKINE VMIP-II

Released:
DOI: 10.2210/pdb1hhv/pdb
PDB entry 1hhv coloured by chain, ensemble of 25 models, front view.
PDB entry 1hhv coloured by chain, ensemble of 25 models, side view.
PDB entry 1hhv coloured by chain, ensemble of 25 models, top view.
Source organism: Human herpesvirus 8 strain GK18
Primary publication:
CCR2 and CCR5 receptor-binding properties of herpesvirus-8 vMIP-II based on sequence analysis and its solution structure.
Shao W, Fernandez E, Sachpatzidis A, Wilken J, Thompson DA, Schweitzer BI, Lolis E
Eur J Biochem 268 2948-59 (2001)
PMID: 11358512

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-189107 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Viral macrophage inflammatory protein 2 Chain: A
Molecule details ›
Chain: A
Length: 74 amino acids
Theoretical weight: 8.46 KDa
Source organism: Human herpesvirus 8 strain GK18
Expression system: Not provided
UniProt:
  • Canonical: Q98157 (Residues: 21-94; Coverage: 100%)
Gene name: ORF K4
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
1 modified residue:
Ligand MSE 1 x MSE

Experiments and Validation Details

Entry percentile scores
Refinement method: TORSIONAL ANGLE MOLECULAR DYNAMICS
Expression system: Not provided

Quick links

Citations

1 review citation

Structure, function, and inhibition of chemokines.
Fernandez et al. (2002)
4 other articles