› 1i2u

Solution NMR

NMR SOLUTION STRUCTURES OF ANTIFUNGAL HELIOMICIN

Released:
DOI: 10.2210/pdb1i2u/pdb
PDB entry 1i2u coloured by chain, ensemble of 18 models, front view.
PDB entry 1i2u coloured by chain, ensemble of 18 models, side view.
PDB entry 1i2u coloured by chain, ensemble of 18 models, top view.
Source organism: Heliothis virescens
Primary publication:
Solution structures of the antifungal heliomicin and a selected variant with both antibacterial and antifungal activities.
Lamberty M, Caille A, Landon C, Tassin-Moindrot S, Hetru C, Bulet P, Vovelle F
Biochemistry 40 11995-2003 (2001)
PMID: 11580275

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Defensin heliomicin Chain: A
Molecule details ›
Chain: A
Length: 44 amino acids
Theoretical weight: 4.8 KDa
Source organism: Heliothis virescens
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P81544 (Residues: 1-44; Coverage: 100%)
Structure domains: Knottin, scorpion toxin-like

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics (DYANA) and energy minimisation (XPLOR)
Expression system: Saccharomyces cerevisiae

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Citations

14 review citations

Anti-microbial peptides: from invertebrates to vertebrates.
Bulet et al. (2004)
13 more

5 mentions without citation

The antimicrobial peptides and their potential clinical applications.
Lei et al. (2019)
4 more