› 1j1q

X-ray diffraction
1.8Å resolution

Structure of Pokeweed Antiviral Protein from Seeds (PAP-S1)

Released:
DOI: 10.2210/pdb1j1q/pdb
PDB entry 1j1q coloured by chain, front view.
PDB entry 1j1q coloured by chain, side view.
PDB entry 1j1q coloured by chain, top view.
Source organism: Phytolacca americana
Entry authors: Watanabe K, Sato E, Honjo E, Motoshima H, Kurokawa H, Mikami B, Monzingo AF, Robertus JD, Fujii H, Hidaka A

Function and Biology Details

Reaction catalysed: 
Endohydrolysis of the N-glycosidic bond at one specific adenosine on the 28S rRNA.
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149929 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Antiviral protein S Chain: A
Molecule details ›
Chain: A
Length: 261 amino acids
Theoretical weight: 29.23 KDa
Source organism: Phytolacca americana
UniProt:
  • Canonical: P23339 (Residues: 1-261; Coverage: 100%)
Sequence domains: Ribosome inactivating protein
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand NAG 1 x NAG
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: PHOTON FACTORY BEAMLINE BL-6B
Spacegroup: I222
Unit cell:
a: 79.1Å b: 85.3Å c: 92.5Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.173 0.173 0.227

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