› 1jq4

Solution NMR

[2Fe-2S] Domain of Methane Monooxygenase Reductase from Methylococcus capsulatus (Bath)

Released:
DOI: 10.2210/pdb1jq4/pdb
PDB entry 1jq4 coloured by chain, ensemble of 10 models, front view.
PDB entry 1jq4 coloured by chain, ensemble of 10 models, side view.
PDB entry 1jq4 coloured by chain, ensemble of 10 models, top view.
Source organism: Methylococcus capsulatus str. Bath
Primary publication:
NMR structure of the [2Fe-2S] ferredoxin domain from soluble methane monooxygenase reductase and interaction with its hydroxylase.
Müller J, Lugovskoy AA, Wagner G, Lippard SJ
Biochemistry 41 42-51 (2002)
PMID: 11772001

Function and Biology Details

Reaction catalysed: 
Methane + NAD(P)H + O(2) = methanol + NAD(P)(+) + H(2)O
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-149816 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Methane monooxygenase component C Chain: A
Molecule details ›
Chain: A
Length: 98 amino acids
Theoretical weight: 10.94 KDa
Source organism: Methylococcus capsulatus str. Bath
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P22868 (Residues: 1-98; Coverage: 28%)
Gene names: MCA1200, mmoC
Sequence domains: 2Fe-2S iron-sulfur cluster binding domain
Structure domains: Ubiquitin-like (UB roll)

Ligands and Environments

1 bound ligand:
Ligand FES 1 x FES
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: NMR
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

7 review citations

Evolution of the soluble diiron monooxygenases.
Leahy et al. (2003)
6 more

8 mentions without citation

Enzymatic oxidation of methane.
Sirajuddin et al. (2015)
7 more