Function and Biology Details
Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
- P-loop containing nucleoside triphosphate hydrolase
- ClpA/B family
- DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
- DNA polymerase III, gamma subunit, domain III
- DNA polymerase III, subunit gamma/tau, helical lid domain
- AAA+ ATPase domain
- DNA polymerase III, subunit gamma/ tau, N-terminal
- DNA polymerase III, delta subunit, C-terminal
4 more domains
Structure analysis Details
Assembly composition:
hetero pentamer (preferred)
Assembly name:
DNA polymerase III (preferred)
PDBe Complex ID:
PDB-CPX-139153 (preferred)
Entry contents:
3 distinct polypeptide molecules
Macromolecules (3 distinct):
DNA polymerase III subunit tau
Molecule details ›
Chains: A, B, C
Length: 373 amino acids
Theoretical weight: 41.51 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Length: 373 amino acids
Theoretical weight: 41.51 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical:
P06710 (Residues: 1-373; Coverage: 58%)
Sequence domains:
- DNA polymerase III, delta subunit
- DNA polymerase III clamp loader subunit, ATPase lid domain
- DNA polymerase III subunits gamma and tau domain III
DNA polymerase III subunit delta
Molecule details ›
Chain: D
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
Sequence domains:
Structure domains:
Length: 343 amino acids
Theoretical weight: 38.75 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
- Canonical: P28630 (Residues: 1-343; Coverage: 100%)
Sequence domains:
Structure domains:
DNA polymerase III subunit delta'
