› 1jsy

X-ray diffraction
2.9Å resolution

Crystal structure of bovine arrestin-2

Released:
DOI: 10.2210/pdb1jsy/pdb
PDB entry 1jsy coloured by chain, front view.
PDB entry 1jsy coloured by chain, side view.
PDB entry 1jsy coloured by chain, top view.
Source organism: Bos taurus
Primary publication:
Scaffolding functions of arrestin-2 revealed by crystal structure and mutagenesis.
Milano SK, Pace HC, Kim YM, Brenner C, Benovic JL
Biochemistry 41 3321-8 (2002)
PMID: 11876640

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-538750 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Beta-arrestin-1 Chain: A
Molecule details ›
Chain: A
Length: 418 amino acids
Theoretical weight: 47.2 KDa
Source organism: Bos taurus
Expression system: Escherichia coli
UniProt:
  • Canonical: P17870 (Residues: 1-418; Coverage: 100%)
Gene name: ARRB1
Sequence domains:
Structure domains:

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: CHESS BEAMLINE F1
Spacegroup: P3221
Unit cell:
a: 78.952Å b: 78.952Å c: 158.924Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.23 0.23 0.238
Expression system: Escherichia coli

Quick links

Citations

36 review citations

Beta-arrestins and cell signaling.
DeWire et al. (2007)
35 more

20 mentions without citation

The Diverse Roles of Arrestin Scaffolds in G Protein-Coupled Receptor Signaling.
Peterson et al. (2017)
19 more