› 1kvz

Solution NMR

Solution Structure of Cytotoxic RC-RNase4

Released:
DOI: 10.2210/pdb1kvz/pdb
PDB entry 1kvz coloured by chain, ensemble of 15 models, front view.
PDB entry 1kvz coloured by chain, ensemble of 15 models, side view.
PDB entry 1kvz coloured by chain, ensemble of 15 models, top view.
Source organism: Lithobates catesbeianus
Primary publication:
Solution structure of the cytotoxic RNase 4 from oocytes of bullfrog Rana catesbeiana.
Hsu CH, Liao YD, Pan YR, Chen LW, Wu SH, Leu YJ, Chen C
J Mol Biol 326 1189-201 (2003)
PMID: 12589762

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-190113 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Ribonuclease A-domain domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12.24 KDa
Source organism: Lithobates catesbeianus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q9DFY6 (Residues: 24-129; Coverage: 100%)
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

4 review citations

Evasion of ribonuclease inhibitor as a determinant of ribonuclease cytotoxicity.
Rutkoski et al. (2008)
3 more