› 1kxw

X-ray diffraction
1.96Å resolution

ANALYSIS OF THE STABILIZATION OF HEN LYSOZYME WITH THE HELIX DIPOLE AND CHARGED SIDE CHAINS

Released:
DOI: 10.2210/pdb1kxw/pdb
PDB entry 1kxw coloured by chain, front view.
PDB entry 1kxw coloured by chain, side view.
PDB entry 1kxw coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Analysis of the stabilization of hen lysozyme by helix macrodipole and charged side chain interaction.
Motoshima H, Mine S, Masumoto K, Abe Y, Iwashita H, Hashimoto Y, Chijiiwa Y, Ueda T, Imoto T
J Biochem 121 1076-81 (1997)
PMID: 9354379

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132831 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
Expression system: Saccharomyces cerevisiae
UniProt:
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 79.16Å b: 79.16Å c: 37.88Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.168 0.168 not available
Expression system: Saccharomyces cerevisiae

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Citations

9 citation in other articles

Reevaluation of stoichiometry and affinity/avidity in interactions between anti-hapten antibodies and mono- or multi-valent antigens.
Oda et al. (2000)
8 more

1 mention without citation

Purification and characterization of avian beta-defensin 11, an antimicrobial peptide of the hen egg.
Hervé-Grépinet et al. (2010)