› 1lzc

X-ray diffraction
1.8Å resolution

DISSECTION OF PROTEIN-CARBOHYDRATE INTERACTIONS IN MUTANT HEN EGG-WHITE LYSOZYME COMPLEXES AND THEIR HYDROLYTIC ACTIVITY

Released:
DOI: 10.2210/pdb1lzc/pdb
PDB entry 1lzc coloured by chain, front view.
PDB entry 1lzc coloured by chain, side view.
PDB entry 1lzc coloured by chain, top view.
Source organism: Gallus gallus
Primary publication:
Dissection of protein-carbohydrate interactions in mutant hen egg-white lysozyme complexes and their hydrolytic activity.
Maenaka K, Matsushima M, Song H, Sunada F, Watanabe K, Kumagai I
J Mol Biol 247 281-93 (1995)
PMID: 7707375

Function and Biology Details

Reaction catalysed: 
Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-132831 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecules (2 distinct):
Lysozyme C Chain: A
Molecule details ›
Chain: A
Length: 129 amino acids
Theoretical weight: 14.33 KDa
Source organism: Gallus gallus
Expression system: Not provided
UniProt:
  • Canonical: P00698 (Residues: 19-147; Coverage: 100%)
Gene name: LYZ
Sequence domains: C-type lysozyme/alpha-lactalbumin family
Structure domains: Lysozyme

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P43212
Unit cell:
a: 78.56Å b: 78.56Å c: 38.49Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.147 not available not available
Expression system: Not provided

Quick links

Citations

4 review citations

Molecular divergence of lysozymes and alpha-lactalbumin.
Qasba et al. (1997)
3 more

9 mentions without citation

Crystal structures of g-type lysozyme from Atlantic cod shed new light on substrate binding and the catalytic mechanism.
Helland et al. (2009)
8 more