› 1q02

Solution NMR

NMR structure of the UBA domain of p62 (SQSTM1)

Released:
DOI: 10.2210/pdb1q02/pdb
PDB entry 1q02 coloured by chain, ensemble of 27 models, front view.
PDB entry 1q02 coloured by chain, ensemble of 27 models, side view.
PDB entry 1q02 coloured by chain, ensemble of 27 models, top view.
Source organism: Homo sapiens
Primary publication:
Structure of the ubiquitin-associated domain of p62 (SQSTM1) and implications for mutations that cause Paget's disease of bone.
Ciani B, Layfield R, Cavey JR, Sheppard PW, Searle MS
J Biol Chem 278 37409-12 (2003)
PMID: 12857745

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-556169 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Sequestosome-1 Chain: A
Molecule details ›
Chain: A
Length: 52 amino acids
Theoretical weight: 5.74 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q13501 (Residues: 387-436; Coverage: 11%)
Gene names: ORCA, OSIL, SQSTM1
Sequence domains: UBA domain
Structure domains: DNA helicase RuvA subunit, C-terminal domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: restrained simulated annealing
Expression system: Escherichia coli

Quick links

Citations

17 review citations

The role of the selective adaptor p62 and ubiquitin-like proteins in autophagy.
Lippai et al. (2014)
16 more

2 mentions without citation

Structure biology of selective autophagy receptors.
Kim et al. (2016)
1 more