› 1qjt

Solution NMR

SOLUTION STRUCTURE OF THE APO EH1 DOMAIN OF MOUSE EPIDERMAL GROWTH FACTOR RECEPTOR SUBSTRATE 15, EPS15

Released:
DOI: 10.2210/pdb1qjt/pdb
PDB entry 1qjt coloured by chain, ensemble of 30 models, front view.
PDB entry 1qjt coloured by chain, ensemble of 30 models, side view.
PDB entry 1qjt coloured by chain, ensemble of 30 models, top view.
Source organism: Mus musculus
Primary publication:
The EH1 domain of Eps15 is structurally classified as a member of the S100 subclass of EF-hand-containing proteins.
Whitehead B, Tessari M, Carotenuto A, van Bergen en Henegouwen PM, Vuister GW
Biochemistry 38 11271-7 (1999)
PMID: 10471276

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-154669 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Epidermal growth factor receptor substrate 15 Chain: A
Molecule details ›
Chain: A
Length: 99 amino acids
Theoretical weight: 10.67 KDa
Source organism: Mus musculus
Expression system: Escherichia coli
UniProt:
  • Canonical: P42567 (Residues: 7-105; Coverage: 11%)
Gene name: Eps15
Sequence domains: Cytoskeletal-regulatory complex EF hand
Structure domains: EF-hand

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 92%
Refinement method: TAD
Expression system: Escherichia coli

Quick links

Citations

7 review citations

Biological basket weaving: formation and function of clathrin-coated vesicles.
Brodsky et al. (2001)
6 more

3 mentions without citation

Endocytic adaptors--social networking at the plasma membrane.
Reider et al. (2011)
2 more