› 1qm1

Solution NMR

Human prion protein fragment 90-230

Released:
DOI: 10.2210/pdb1qm1/pdb
PDB entry 1qm1 coloured by chain, ensemble of 20 models, front view.
PDB entry 1qm1 coloured by chain, ensemble of 20 models, side view.
PDB entry 1qm1 coloured by chain, ensemble of 20 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR solution structure of the human prion protein.
Zahn R, Liu A, Lührs T, Riek R, von Schroetter C, López García F, Billeter M, Calzolai L, Wider G, Wüthrich K
Proc Natl Acad Sci U S A 97 145-50 (2000)
PMID: 10618385

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-137455 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Major prion protein Chain: A
Molecule details ›
Chain: A
Length: 143 amino acids
Theoretical weight: 16.23 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P04156 (Residues: 90-230; Coverage: 61%)
Gene names: ALTPRP, PRIP, PRNP, PRP
Sequence domains: Prion/Doppel alpha-helical domain
Structure domains: Prion/Doppel protein, beta-ribbon domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

128 review citations

3D domain swapping: as domains continue to swap.
Liu et al. (2002)
127 more

15 mentions without citation

A structural overview of the vertebrate prion proteins.
Pastore et al. (2007)
14 more