› 1qxq

Solution NMR

STRUCTURE OF AN INDOLICIDIN PEPTIDE DERIVATIVE WITH HIGHER CHARGE

Released:
DOI: 10.2210/pdb1qxq/pdb
PDB entry 1qxq coloured by chain, ensemble of 12 models, front view.
PDB entry 1qxq coloured by chain, ensemble of 12 models, side view.
PDB entry 1qxq coloured by chain, ensemble of 12 models, top view.
Source organism: Bos taurus
Primary publication:
Structure-based design of an indolicidin peptide analogue with increased protease stability.
Rozek A, Powers JP, Friedrich CL, Hancock RE
Biochemistry 42 14130-8 (2003)
PMID: 14640680

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-152537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Cathelicidin-4 Chain: A
Molecule details ›
Chain: A
Length: 14 amino acids
Theoretical weight: 1.88 KDa
Source organism: Bos taurus
Expression system: Not provided
UniProt:
  • Canonical: P33046 (Residues: 134-144; Coverage: 10%)
Gene name: CATHL4

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY AND SIMULATED ANNEALING
Expression system: Not provided

Quick links

Citations

27 review citations

Peptide antimicrobial agents.
Jenssen et al. (2006)
26 more

1 mention without citation

Tumor cell membrane-targeting cationic antimicrobial peptides: novel insights into mechanisms of action and therapeutic prospects.
Baxter et al. (2017)