› 1s19

X-ray diffraction
2.1Å resolution

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-145848 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Vitamin D3 receptor Chain: A
Molecule details ›
Chain: A
Length: 263 amino acids
Theoretical weight: 29.81 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P11473 (Residues: 118-427; Coverage: 61%)
Gene names: NR1I1, VDR
Sequence domains: Ligand-binding domain of nuclear hormone receptor
Structure domains: Retinoid X Receptor

Ligands and Environments

1 bound ligand:
Ligand MC9 1 x MC9
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ESRF BEAMLINE BM14
Spacegroup: P212121
Unit cell:
a: 45.248Å b: 52.55Å c: 132.909Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.179 0.179 0.214
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

15 review citations

Vitamin D: Metabolism, Molecular Mechanism of Action, and Pleiotropic Effects.
Christakos et al. (2016)
14 more

11 mentions without citation

Variability in docking success rates due to dataset preparation.
Corbeil et al. (2012)
10 more