› 1sxd

Solution NMR

Solution Structure of the Pointed (PNT) Domain from mGABPa

Released:
DOI: 10.2210/pdb1sxd/pdb
PDB entry 1sxd coloured by chain, ensemble of 14 models, front view.
PDB entry 1sxd coloured by chain, ensemble of 14 models, side view.
PDB entry 1sxd coloured by chain, ensemble of 14 models, top view.
Source organism: Mus musculus
Primary publication:
Diversity in structure and function of the Ets family PNT domains.
Mackereth CD, Schärpf M, Gentile LN, MacIntosh SE, Slupsky CM, McIntosh LP
J Mol Biol 342 1249-64 (2004)
PMID: 15351649

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-169414 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
GA-binding protein alpha chain Chain: A
Molecule details ›
Chain: A
Length: 91 amino acids
Theoretical weight: 10.75 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q00422 (Residues: 168-254; Coverage: 19%)
Gene names: E4tf1a, Gabpa
Sequence domains: Sterile alpha motif (SAM)/Pointed domain
Structure domains: Transcription Factor, Ets-1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

12 review citations

The many faces of the helix-turn-helix domain: transcription regulation and beyond.
Aravind et al. (2005)
11 more

2 mentions without citation

Identification and structural characterization of a CBP/p300-binding domain from the ETS family transcription factor GABP alpha.
Kang et al. (2008)
1 more