1t47

X-ray diffraction
2.5Å resolution

Structure of fe2-HPPD bound to NTBC

Released:
Model geometry
Fit model/data

Function and Biology Details

Structure analysis Details

Assembly composition:
homo dimer (preferred)
PDBe Complex ID:
PDB-CPX-176059 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
4-hydroxyphenylpyruvate dioxygenase Chains: A, B
Molecule details ›
Chains: A, B
Length: 381 amino acids
Theoretical weight: 41.91 KDa
Source organism: Streptomyces avermitilis
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q53586 (Residues: 1-381; Coverage: 100%)
Gene names: SAV_5149, hpd
Sequence domains: Glyoxalase/Bleomycin resistance protein/Dioxygenase superfamily
Structure domains: 2,3-Dihydroxybiphenyl 1,2-Dioxygenase, domain 1

Ligands and Environments

2 bound ligands:
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: APS BEAMLINE 19-ID, APS BEAMLINE 19-BM
Spacegroup: P21212
Unit cell:
a: 81.288Å b: 162.045Å c: 56.15Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.184 0.178 0.238
Expression system: Escherichia coli BL21(DE3)