› 1txj

X-ray diffraction
2Å resolution

Crystal structure of translationally controlled tumour-associated protein (TCTP) from Plasmodium knowlesi

Released:
DOI: 10.2210/pdb1txj/pdb
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Source organism: Plasmodium knowlesi
Primary publication:
Genome-scale protein expression and structural biology of Plasmodium falciparum and related Apicomplexan organisms.
Vedadi M, Lew J, Artz J, Amani M, Zhao Y, Dong A, Wasney GA, Gao M, Hills T, Brokx S, Qiu W, Sharma S, Diassiti A, Alam Z, Melone M, Mulichak A, Wernimont A, Bray J, Loppnau P, Plotnikova O, Newberry K, Sundararajan E, Houston S, Walker J, Tempel W, Bochkarev A, Kozieradzki I, Edwards A, Arrowsmith C, Roos D, Kain K, Hui R
Mol Biochem Parasitol 151 100-10 (2007)
PMID: 17125854

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160850 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translationally-controlled tumor protein homolog Chain: A
Molecule details ›
Chain: A
Length: 171 amino acids
Theoretical weight: 19.88 KDa
Source organism: Plasmodium knowlesi
Expression system: Escherichia coli
UniProt:
  • Canonical: P84152 (Residues: 1-171; Coverage: 100%)
Gene name: TCTP
Sequence domains: Translationally controlled tumour protein
Structure domains: Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU300
Spacegroup: P65
Unit cell:
a: 86.633Å b: 86.633Å c: 55.636Å
α: 90° β: 90° γ: 120°
R-values:
R R work R free
0.199 0.199 0.234
Expression system: Escherichia coli

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Citations

34 review citations

Structure-based insights into the catalytic power and conformational dexterity of peroxiredoxins.
Hall et al. (2011)
33 more

3 mentions without citation

Towards automated crystallographic structure refinement with phenix.refine.
Afonine et al. (2012)
2 more

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