› 1utc

X-ray diffraction
2.3Å resolution

Clathrin terminal domain complexed with TLPWDLWTT

Released:
DOI: 10.2210/pdb1utc/pdb
PDB entry 1utc coloured by chain, front view.
PDB entry 1utc coloured by chain, side view.
PDB entry 1utc coloured by chain, top view.
Source organisms:
Primary publication:
Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller.
Miele AE, Watson PJ, Evans PR, Traub LM, Owen DJ
Nat Struct Mol Biol 11 242-8 (2004)
PMID: 14981508

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-155944 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Clathrin heavy chain 1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 363 amino acids
Theoretical weight: 40.4 KDa
Source organism: Bos taurus
Expression system: Escherichia coli DH5[alpha]
UniProt:
  • Canonical: P49951 (Residues: 1-363; Coverage: 22%)
Gene name: CLTC
Sequence domains:
Structure domains: Clathrin heavy-chain terminal domain
Amphiphysin Chains: P, Q
Molecule details ›
Chains: P, Q
Length: 9 amino acids
Theoretical weight: 1.13 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P49418 (Residues: 379-387; Coverage: 1%)
Gene names: AMPH, AMPH1

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SRS BEAMLINE PX9.6
Spacegroup: P41212
Unit cell:
a: 61.301Å b: 61.301Å c: 420.52Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.197 0.194 0.253
Expression systems:
  • Escherichia coli DH5[alpha]
  • Not provided

Quick links

Citations

22 review citations

Ubiquitin-binding domains.
Hicke et al. (2005)
21 more

15 mentions without citation

The role of clathrin in mitotic spindle organisation.
Royle SJ. (2012)
14 more