› 1v2a

X-ray diffraction
2.15Å resolution

Glutathione S-transferase 1-6 from Anopheles dirus species B

Released:
DOI: 10.2210/pdb1v2a/pdb
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PDB entry 1v2a coloured by chain, front view.
PDB entry 1v2a coloured by chain, side view.
PDB entry 1v2a coloured by chain, top view.
Source organism: Anopheles dirus
Primary publication:
Identification, characterization and structure of a new Delta class glutathione transferase isoenzyme.
Udomsinprasert R, Pongjaroenkit S, Wongsantichon J, Oakley AJ, Prapanthadara LA, Wilce MC, Ketterman AJ
Biochem J 388 763-71 (2005)
PMID: 15717864

Function and Biology Details

Reaction catalysed: 
RX + glutathione = HX + R-S-glutathione
Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domains:

Structure analysis Details

Assemblies composition:
homo dimer (preferred)
homo tetramer
Assembly name:
PDBe Complex ID:
PDB-CPX-189629 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
glutathione transferase Chains: A, B, C, D
Molecule details ›
Chains: A, B, C, D
Length: 210 amino acids
Theoretical weight: 24.16 KDa
Source organism: Anopheles dirus
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BHB0 (Residues: 1-210; Coverage: 100%)
Gene name: gst1-6
Sequence domains:
Structure domains:

Ligands and Environments


Cofactor: Ligand GTS 4 x GTS
No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P212121
Unit cell:
a: 48.203Å b: 88.136Å c: 200.446Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.234 0.234 0.284
Expression system: Escherichia coli

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Citations

7 review citations

Computational methods in drug discovery.
Sliwoski et al. (2014)
6 more

3 mentions without citation

Antenna-specific glutathione S-transferase in male silkmoth Bombyx mori.
Tan et al. (2014)
2 more

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