› 1wlh

X-ray diffraction
2.8Å resolution

Molecular structure of the rod domain of Dictyostelium filamin

Released:
DOI: 10.2210/pdb1wlh/pdb
PDB entry 1wlh coloured by chain, front view.
PDB entry 1wlh coloured by chain, side view.
PDB entry 1wlh coloured by chain, top view.
Source organism: Dictyostelium discoideum
Primary publication:
Molecular structure of the rod domain of dictyostelium filamin.
Popowicz GM, Müller R, Noegel AA, Schleicher M, Huber R, Holak TA
J Mol Biol 342 1637-46 (2004)
PMID: 15364587

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
homo dimer (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-146596 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Gelation factor Chains: A, B
Molecule details ›
Chains: A, B
Length: 311 amino acids
Theoretical weight: 32.72 KDa
Source organism: Dictyostelium discoideum
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P13466 (Residues: 547-857; Coverage: 36%)
Gene names: DDB_G0269100, abpC
Sequence domains: Filamin/ABP280 repeat
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SLS BEAMLINE X06SA
Spacegroup: P21
Unit cell:
a: 56.32Å b: 61.67Å c: 119.03Å
α: 90° β: 104.1° γ: 90°
R-values:
R R work R free
0.258 0.257 0.263
Expression system: Escherichia coli BL21

Quick links

Citations

5 review citations

Filamins: promiscuous organizers of the cytoskeleton.
Popowicz et al. (2006)
4 more

7 mentions without citation

Evolutionarily conserved human targets of adenosine to inosine RNA editing.
Levanon et al. (2005)
6 more