› 1ypz

X-ray diffraction
3.4Å resolution

Immune receptor

Released:
DOI: 10.2210/pdb1ypz/pdb
Model geometry
Fit model/data
Data not deposited
PDB entry 1ypz coloured by chain, front view.
PDB entry 1ypz coloured by chain, side view.
PDB entry 1ypz coloured by chain, top view.
Source organisms:
Primary publication:
Structure of a gammadelta T cell receptor in complex with the nonclassical MHC T22.
Adams EJ, Chien YH, Garcia KC
Science 308 227-31 (2005)
PMID: 15821084

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
hetero octamer (preferred)
PDBe Complex ID:
PDB-CPX-209281 (preferred)
Entry contents:
4 distinct polypeptide molecules
Macromolecules (7 distinct):
Ig-like domain-containing protein Chains: A, C
Molecule details ›
Chains: A, C
Length: 260 amino acids
Theoretical weight: 29.92 KDa
Source organism: Mus musculus
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q9BCZ1 (Residues: 29-288; Coverage: 80%)
Gene name: H2-T22
Sequence domains:
Structure domains:
Beta-2-microglobulin Chains: B, D
Molecule details ›
Chains: B, D
Length: 102 amino acids
Theoretical weight: 12.03 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: P61769 (Residues: 21-119; Coverage: 100%)
Gene names: B2M, CDABP0092, HDCMA22P
Sequence domains: Immunoglobulin C1-set domain
Structure domains: Immunoglobulins
T cell receptor delta Chains: E, G
T-cell receptor gamma chain C region DFL12 Chains: F, H

Ligands and Environments

Carbohydrate polymer : NEW Components: NAG, MAN
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG
Carbohydrate polymer
Carbohydrate polymer : NEW Components: NAG, FUC
Carbohydrate polymer
No bound ligands
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this entry.
Spacegroup: P212121
Unit cell:
a: 110.53Å b: 113.05Å c: 167.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.264 0.264 0.33
Expression system: Spodoptera frugiperda

Quick links

Citations

64 review citations

Engineered antibody fragments and the rise of single domains.
Holliger et al. (2005)
63 more

10 mentions without citation

Structural biology of the T-cell receptor: insights into receptor assembly, ligand recognition, and initiation of signaling.
Wucherpfennig et al. (2010)
9 more