Function and Biology Details
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Talin-1 and Vinculin (preferred)
PDBe Complex ID:
PDB-CPX-146030 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Vinculin
Molecule details ›
Chain: A
Length: 279 amino acids
Theoretical weight: 31.2 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Length: 279 amino acids
Theoretical weight: 31.2 KDa
Source organism: Gallus gallus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical:
P12003 (Residues: 2-259; Coverage: 23%)
Sequence domains: Vinculin family
Structure domains: Alpha-catenin/vinculin-like
Talin-1
Molecule details ›
Chain: B
Length: 25 amino acids
Theoretical weight: 2.83 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 25 amino acids
Theoretical weight: 2.83 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: P26039 (Residues: 1628-1652; Coverage: 1%)
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
ESRF BEAMLINE ID14-3
Spacegroup:
P21212
Expression systems:
- Escherichia coli BL21(DE3)
- Not provided
