1b0w

X-ray diffraction
1.8Å resolution

Structural comparison of amyloidogenic light chain dimer in two crystal forms with nonamyloidogenic counterparts

Released:

Function and Biology Details

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134442 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Immunoglobulin kappa variable 1-33 Chains: A, B, C
Molecule details ›
Chains: A, B, C
Length: 108 amino acids
Theoretical weight: 11.95 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01594 (Residues: 23-117; Coverage: 100%)
Gene name: IGKV1-33
Sequence domains: Immunoglobulin V-set domain
Structure domains: Immunoglobulins

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: C2221
Unit cell:
a: 82.04Å b: 142.11Å c: 77.86Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.226 0.226 0.299
Expression system: Escherichia coli