Function and Biology

STRUCTURAL ANALYSIS OF PHOSDUCIN AND ITS PHOSPHORYLATION-REGULATED INTERACTION WITH TRANSDUCIN BETA-GAMMA

Sequence families

Pfam Protein families (Pfam)
PF00400
Domain description: WD domain, G-beta repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 1b9y contains 7 copies of Pfam domain PF00400 (WD domain, G-beta repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 7 copies in chain A.

PF02114
Domain description: Phosducin
Occurring in:
  1. Phosducin
The deposited structure of PDB entry 1b9y contains 1 copy of Pfam domain PF02114 (Phosducin) in Phosducin. Showing 1 copy in chain C.

PF00631
Domain description: GGL domain
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
The deposited structure of PDB entry 1b9y contains 1 copy of Pfam domain PF00631 (GGL domain) in Guanine nucleotide-binding protein G(T) subunit gamma-T1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR001680
Domain description: WD40 repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR001200
Domain description: Phosducin
Occurring in:
  1. Phosducin
IPR015898
Domain description: G-protein gamma-like domain
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
IPR001770
Domain description: G-protein, gamma subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
IPR001632
Domain description: G-protein, beta subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR020472
Domain description: G-protein beta WD-40 repeat
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR023196
Domain description: Phosducin, N-terminal domain superfamily
Occurring in:
  1. Phosducin
IPR036284
Domain description: G-protein gamma-like domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
IPR036249
Domain description: Thioredoxin-like superfamily
Occurring in:
  1. Phosducin
IPR024253
Domain description: Phosducin, thioredoxin-like domain
Occurring in:
  1. Phosducin
IPR019775
Domain description: WD40 repeat, conserved site
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR036322
Domain description: WD40-repeat-containing domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR016346
Domain description: Guanine nucleotide-binding protein, beta subunit
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
IPR015943
Domain description: WD40/YVTN repeat-like-containing domain superfamily
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1

Structure domains

CATH CATH domains
3.40.30.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Glutaredoxin
Homology: Glutaredoxin
Occurring in:
  1. Phosducin
The deposited structure of PDB entry 1b9y contains 1 copy of CATH domain 3.40.30.10 (Glutaredoxin) in Phosducin. Showing 1 copy in chain C.
1.10.168.10
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Phosducin; domain 2
Homology: Phosducin, domain 2
Occurring in:
  1. Phosducin
The deposited structure of PDB entry 1b9y contains 1 copy of CATH domain 1.10.168.10 (Phosducin; domain 2) in Phosducin. Showing 1 copy in chain C.
4.10.260.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: G Protein Gi Gamma 2
Homology: Transducin (heterotrimeric G protein), gamma chain
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
The deposited structure of PDB entry 1b9y contains 1 copy of CATH domain 4.10.260.10 (G Protein Gi Gamma 2) in Guanine nucleotide-binding protein G(T) subunit gamma-T1. Showing 1 copy in chain B.
2.130.10.10
Class: Mainly Beta
Architecture: 7 Propeller
Topology: Methylamine Dehydrogenase; Chain H
Homology: YVTN repeat-like/Quinoprotein amine dehydrogenase
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 1b9y contains 1 copy of CATH domain 2.130.10.10 (Methylamine Dehydrogenase; Chain H) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 1 copy in chain A.
SCOP SCOP annotations
52888
Class: Alpha and beta proteins (a/b)
Fold: Thioredoxin fold
Superfamily: Thioredoxin-like
Occurring in:
  1. Phosducin
The deposited structure of PDB entry 1b9y contains 1 copy of SCOP domain 52888 (Phosducin) in Phosducin. Showing 1 copy in chain C.
48671
Class: All alpha proteins
Fold: Non-globular all-alpha subunits of globular proteins
Superfamily: Transducin (heterotrimeric G protein), gamma chain
Occurring in:
  1. Guanine nucleotide-binding protein G(T) subunit gamma-T1
The deposited structure of PDB entry 1b9y contains 1 copy of SCOP domain 48671 (Transducin (heterotrimeric G protein), gamma chain) in Guanine nucleotide-binding protein G(T) subunit gamma-T1. Showing 1 copy in chain B.
50979
Class: All beta proteins
Fold: 7-bladed beta-propeller
Superfamily: WD40 repeat-like
Occurring in:
  1. Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1
The deposited structure of PDB entry 1b9y contains 1 copy of SCOP domain 50979 (WD40-repeat) in Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1. Showing 1 copy in chain A.