Function and Biology Details
Reaction catalysed:
5,10-methylenetetrahydrofolate + dUMP = dihydrofolate + dTMP
Biochemical function:
Biological process:
Cellular component:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Thymidylate synthase (preferred)
PDBe Complex ID:
PDB-CPX-132544 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Thymidylate synthase
Molecule details ›
Chain: A
Length: 316 amino acids
Theoretical weight: 36.52 KDa
Source organism: Lacticaseibacillus casei
Expression system: Escherichia coli
UniProt:
Sequence domains: Thymidylate synthase
Structure domains: Thymidylate synthase/dCMP hydroxymethylase domain
Length: 316 amino acids
Theoretical weight: 36.52 KDa
Source organism: Lacticaseibacillus casei
Expression system: Escherichia coli
UniProt:
- Canonical:
P00469 (Residues: 1-316; Coverage: 100%)
Sequence domains: Thymidylate synthase
Structure domains: Thymidylate synthase/dCMP hydroxymethylase domain
