1cf0

X-ray diffraction
2.2Å resolution

HUMAN PLATELET PROFILIN COMPLEXED WITH AN L-PRO10-IODOTYROSINE PEPTIDE

Released:
Source organism: Homo sapiens

Function and Biology Details

Structure analysis Details

Assemblies composition:
hetero dimer (preferred)
monomeric
Assembly name:
PDBe Complex ID:
PDB-CPX-139731 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Profilin-1 Chains: A, B
Molecule details ›
Chains: A, B
Length: 138 amino acids
Theoretical weight: 14.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P07737 (Residues: 3-140; Coverage: 99%)
Gene name: PFN1
Sequence domains: Profilin
Structure domains: Dynein light chain 2a, cytoplasmic
PROTEIN (L-PRO10-IODOTYROSINE) Chain: C
Molecule details ›
Chain: C
Length: 9 amino acids
Theoretical weight: 1.08 KDa
Source organism: Homo sapiens
Expression system: Not provided

Ligands and Environments

No bound ligands
1 modified residue:

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RU200
Spacegroup: P21212
Unit cell:
a: 68.29Å b: 97.65Å c: 38.97Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.21 0.21 0.31
Expression systems:
  • Escherichia coli BL21(DE3)
  • Not provided