› 1cou

Solution NMR

ANTICOAGULANT PROTEIN FROM THE NEMATODE ANCYLOSTOMA CANINUM

Released:
DOI: 10.2210/pdb1cou/pdb
PDB entry 1cou coloured by chain, ensemble of 18 models, front view.
PDB entry 1cou coloured by chain, ensemble of 18 models, side view.
PDB entry 1cou coloured by chain, ensemble of 18 models, top view.
Source organism: Ancylostoma caninum
Primary publication:
Inherent flexibility in a potent inhibitor of blood coagulation, recombinant nematode anticoagulant protein c2.
Duggan BM, Dyson HJ, Wright PE
Eur J Biochem 265 539-48 (1999)
PMID: 10504384

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-172614 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
TIL domain-containing protein Chain: A
Molecule details ›
Chain: A
Length: 85 amino acids
Theoretical weight: 9.76 KDa
Source organism: Ancylostoma caninum
Expression system: Komagataella pastoris
UniProt:
  • Canonical: Q16938 (Residues: 8-91; Coverage: 92%)
Sequence domains: Trypsin Inhibitor like cysteine rich domain
Structure domains: Laminin

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: molecular dynamics
Expression system: Komagataella pastoris

Quick links

Citations

11 review citations

A new spin on protein dynamics.
Columbus et al. (2002)
10 more

2 mentions without citation

Critical nucleation size in the folding of small apparently two-state proteins.
Bai et al. (2004)
1 more