› 1crb

X-ray diffraction
2.1Å resolution

CRYSTALLOGRAPHIC STUDIES ON A FAMILY OF CELLULAR LIPOPHILIC TRANSPORT PROTEINS. REFINEMENT OF P2 MYELIN PROTEIN AND THE STRUCTURE DETERMINATION AND REFINEMENT OF CELLULAR RETINOL-BINDING PROTEIN IN COMPLEX WITH ALL-TRANS-RETINOL

Released:
DOI: 10.2210/pdb1crb/pdb
PDB entry 1crb coloured by chain, front view.
PDB entry 1crb coloured by chain, side view.
PDB entry 1crb coloured by chain, top view.
Source organism: Rattus rattus
Primary publication:
Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with all-trans-retinol.
Cowan SW, Newcomer ME, Jones TA
J Mol Biol 230 1225-46 (1993)
PMID: 7683727

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-136052 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Retinol-binding protein 1 Chain: A
Molecule details ›
Chain: A
Length: 134 amino acids
Theoretical weight: 15.72 KDa
Source organism: Rattus rattus
Expression system: Not provided
UniProt:
  • Canonical: P02696 (Residues: 2-135; Coverage: 99%)
Gene names: Rbp-1, Rbp1
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

2 bound ligands:
Ligand CD 2 x CD
Ligand RTL 1 x RTL
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: P212121
Unit cell:
a: 40.09Å b: 47.39Å c: 69.34Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.188 0.188 0.248
Expression system: Not provided

Quick links

Citations

21 review citations

Retinoid-binding proteins: mediators of retinoid action.
Noy N. (2000)
20 more

14 mentions without citation

Chemical shift prediction for protein structure calculation and quality assessment using an optimally parameterized force field.
Nielsen et al. (2012)
13 more