PDB 1cwc structure summary ‹ Protein Data Bank in Europe (PDBe)

Function and Biology Details

Reaction catalysed:

Peptidylproline (omega=180) = peptidylproline (omega=0)

Biochemical function:

heparan sulfate binding

Biological process:

regulation of apoptotic signaling pathway

Cellular component:

ficolin-1-rich granule lumen

Sequence domains:

Structure domain:

Cyclophilin (peptidylprolyl isomerase)

Structure analysis Details

Assembly composition:

hetero dimer (preferred)

Assembly name:

Peptidyl-prolyl cis-trans isomerase A and peptide (preferred)

PDBe Complex ID:

PDB-CPX-158777 (preferred)

Entry contents:

2 distinct polypeptide molecules

Macromolecules (2 distinct):

Peptidyl-prolyl cis-trans isomerase A Chain: A

Molecule details ›

Chain: A
Length: 165 amino acids
Theoretical weight: 18.04 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:

Canonical: P62937 (Residues: 1-165; Coverage: 100%)

Gene names: CYPA, PPIA
Sequence domains: Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD
Structure domains: Cyclophilin-like

CYCLOSPORIN A Chain: C

Molecule details ›

Chain: C
Length: 11 amino acids
Theoretical weight: 1.23 KDa
Source organism: Tolypocladium inflatum
Expression system: Not provided