EC 2.7.10.2: Non-specific protein-tyrosine kinase
Reaction catalysed:
ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
Systematic name:
ATP:[protein]-L-tyrosine O-phosphotransferase (non-specific)
Alternative Name(s):
- ABL
- ABL1
- ABL2
- ABLL
- ACK1
- ACK2
- AGMX1
- ARG
- ATK
- ATP:protein-tyrosine O-phosphotransferase
- BLK
- BMX
- BRK
- BTK
- BTKL
- Bmk
- Bruton's tyrosine kinase
- Bsk
- CAKb
- CHK
- CSK
- CTK
- CYL
- Cdgip
- Cytoplasmic protein tyrosine kinase
- EMT
- ETK
- FAK
- FAK2
- FER
- FES
- FGR
- FPS
- FRK
- FYN
- Fadk
- Fert1/2
- Focal adhesion kinase
- HCK
- HCTK
- HYL
- IMD1
- ITK
- IYK
- JAK1
- JAK2
- JAK3
- JTK1
- JTK9
- Janus kinase 1
- Janus kinase 2
- Janus kinase 3
- L-JAK
- LCK
- LSK
- LYN
- MATK
- Ntk
- P60c-src protein tyrosine kinase
- PKB
- PSCTK
- PSCTK1
- PSCTK2
- PSCTK4
- PSCTK5
- PTK2
- PTK2B
- PTK6
- PYK2
- Protein-tyrosine kinase
- RAFTK
- RAK
- Rlk
- SLK
- SRC
- SRC2
- SRK
- SRM
- SRMS
- STD
- SYK
- SYN
- Sik
- TEC
- TNK1
- TXK
- TYK2
- TYK3
- Tck
- Tsk
- YES1
- YK2
- ZAP70
GO terms
Biochemical function:
- not assigned
Biological process:
- not assigned
Cellular component:
- not assigned
Protein family (Pfam)![The deposited structure of PDB entry 1cwd contains 1 copy of Pfam domain PF00017 (SH2 domain) in Tyrosine-protein kinase Lck. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1cwd_1_L_Pfam_PF00017_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1cwd</span> contains 1 copy of Pfam domain <span class='highlight'>PF00017 (SH2 domain)</span> in <span class='highlight'>Tyrosine-protein kinase Lck</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")
InterPro annotations
CATH domain![The deposited structure of PDB entry 1cwd contains 1 copy of CATH domain 3.30.505.10 (SHC Adaptor Protein) in Tyrosine-protein kinase Lck. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1cwd_1_L_CATH_3.30.505.10_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1cwd</span> contains 1 copy of CATH domain <span class='highlight'>3.30.505.10 (SHC Adaptor Protein)</span> in <span class='highlight'>Tyrosine-protein kinase Lck</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")
SCOP annotation![The deposited structure of PDB entry 1cwd contains 1 copy of SCOP domain 55551 (SH2 domain) in Tyrosine-protein kinase Lck. Showing 1 copy in chain A [auth L].](https://www.ebi.ac.uk/pdbe/static/entry/1cwd_1_L_SCOP_55551_image-200x200.png "The deposited structure of PDB entry <span class='highlight'>1cwd</span> contains 1 copy of SCOP domain <span class='highlight'>55551 (SH2 domain)</span> in <span class='highlight'>Tyrosine-protein kinase Lck</span>. Showing 1 copy in chain <span class='highlight'>A [auth L]</span>.")