› 1d6b

Solution NMR

SOLUTION STRUCTURE OF DEFENSIN-LIKE PEPTIDE-2 (DLP-2) FROM PLATYPUS VENOM

Released:
DOI: 10.2210/pdb1d6b/pdb
PDB entry 1d6b coloured by chain, ensemble of 20 models, front view.
PDB entry 1d6b coloured by chain, ensemble of 20 models, side view.
PDB entry 1d6b coloured by chain, ensemble of 20 models, top view.
Source organism: Ornithorhynchus anatinus
Primary publication:
Defensin-like peptide-2 from platypus venom: member of a class of peptides with a distinct structural fold.
Torres AM, de Plater GM, Doverskog M, Birinyi-Strachan LC, Nicholson GM, Gallagher CH, Kuchel PW
Biochem J 348 Pt 3 649-56 (2000)
PMID: 10839998

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-160605 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Defensin-like peptide 2/4 Chain: A
Molecule details ›
Chain: A
Length: 42 amino acids
Theoretical weight: 5.12 KDa
Source organism: Ornithorhynchus anatinus
UniProt:
  • Canonical: P82140 (Residues: 25-66; Coverage: 96%)
Sequence domains: Defensin-like peptide family
Structure domains: Anthopleurin-A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: DISTANCE GEOMETRY, SIMULATED ANNEALING, MOLECULAR DYNAMICS, TORSION ANGLE DYNAMICS

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Citations

10 review citations

Defensins of vertebrate animals.
Lehrer et al. (2002)
9 more

4 mentions without citation

The antimicrobial peptides and their potential clinical applications.
Lei et al. (2019)
3 more