› 1dem

Solution NMR

PROTEINASE INHIBITOR HOMOLOGUES AS POTASSIUM CHANNEL BLOCKERS

Released:
DOI: 10.2210/pdb1dem/pdb
PDB entry 1dem coloured by chain, front view.
PDB entry 1dem coloured by chain, side view.
PDB entry 1dem coloured by chain, top view.
Source organism: Dendroaspis polylepis polylepis
Primary publication:
Proteinase inhibitor homologues as potassium channel blockers.
Lancelin JM, Foray MF, Poncin M, Hollecker M, Marion D
Nat Struct Biol 1 246-50 (1994)
PMID: 7544683

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133767 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Kunitz-type serine protease inhibitor homolog dendrotoxin I Chain: A
Molecule details ›
Chain: A
Length: 60 amino acids
Theoretical weight: 7.17 KDa
Source organism: Dendroaspis polylepis polylepis
Expression system: Not provided
UniProt:
  • Canonical: P00979 (Residues: 1-60; Coverage: 100%)
Sequence domains: Kunitz/Bovine pancreatic trypsin inhibitor domain
Structure domains: Pancreatic trypsin inhibitor Kunitz domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

8 review citations

Twenty years of dendrotoxins.
Harvey AL. (2001)
7 more

7 mentions without citation

Snake Venom: A Promising Source of Neurotoxins Targeting Voltage-Gated Potassium Channels.
AlShammari et al. (2023)
6 more