1dfj

X-ray diffraction
2.5Å resolution

RIBONUCLEASE INHIBITOR COMPLEXED WITH RIBONUCLEASE A

Released:

Function and Biology Details

Reaction catalysed:
(1a) an (RNA) containing cytidine = an (RNA)-3'-cytidine-2',3'-cyclophosphate + a 5'-hydroxy-ribonucleotide-3'-(RNA)
Biochemical function:
Biological process:
Cellular component:

Structure analysis Details

Assembly composition:
hetero dimer (preferred)
PDBe Complex ID:
PDB-CPX-145451 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Ribonuclease pancreatic Chain: E
Molecule details ›
Chain: E
Length: 124 amino acids
Theoretical weight: 13.71 KDa
Source organism: Bos taurus
UniProt:
  • Canonical: P61823 (Residues: 27-150; Coverage: 100%)
Gene names: RNASE1, RNS1
Sequence domains: Pancreatic ribonuclease
Structure domains: Ribonuclease A-like domain
Ribonuclease inhibitor Chain: I
Molecule details ›
Chain: I
Length: 457 amino acids
Theoretical weight: 49.09 KDa
Source organism: Sus scrofa
UniProt:
  • Canonical: P10775 (Residues: 1-456; Coverage: 100%)
Gene names: RI, RNH, RNH1
Sequence domains:
Structure domains: Ribonuclease Inhibitor

Ligands and Environments

1 bound ligand:
No modified residues

Experiments and Validation Details

Entry percentile scores
Spacegroup: I4
Unit cell:
a: 133.3Å b: 133.3Å c: 86.7Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.194 0.194 not available