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SOLUTION STRUCTURE OF THE THETA SUBUNIT OF DNA POLYMERASE III

Source organism: Escherichia coli
Biochemical function: DNA polymerase activity
Biological process: DNA biosynthetic process
Cellular component: DNA polymerase III, core complex

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EC 2.7.7.7: DNA-directed DNA polymerase

Reaction catalysed:
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
Systematic name:
Deoxynucleoside-triphosphate:DNA deoxynucleotidyltransferase (DNA-directed)
Alternative Name(s):
  • DNA duplicase
  • DNA nucleotidyltransferase
  • DNA nucleotidyltransferase (DNA-directed)
  • DNA polymerase
  • DNA polymerase I
  • DNA polymerase II
  • DNA polymerase III
  • DNA polymerase alpha
  • DNA polymerase beta
  • DNA polymerase gamma
  • DNA replicase
  • DNA-dependent DNA polymerase
  • Deoxynucleate polymerase
  • Deoxyribonucleate nucleotidyltransferase
  • Deoxyribonucleic acid duplicase
  • Deoxyribonucleic acid polymerase
  • Deoxyribonucleic duplicase
  • Deoxyribonucleic polymerase
  • Deoxyribonucleic polymerase I
  • Duplicase
  • Klenow fragment
  • Sequenase
  • Taq DNA polymerase
  • Taq Pol I
  • Tca DNA polymerase

GO terms

Sequence family

Pfam Protein family (Pfam)
PF06440
Domain description: DNA polymerase III, theta subunit
Occurring in:
  1. DNA polymerase III subunit theta
The deposited structure of PDB entry 1du2 contains 1 copy of Pfam domain PF06440 (DNA polymerase III, theta subunit) in DNA polymerase III subunit theta. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR009052
Domain description: DNA polymerase III-theta, bacterial
Occurring in:
  1. DNA polymerase III subunit theta
IPR036745
Domain description: DNA polymerase III-theta superfamily
Occurring in:
  1. DNA polymerase III subunit theta

Structure domain

CATH CATH domain
1.20.58.250
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Methane Monooxygenase Hydroxylase; Chain G, domain 1
Homology: DNA polymerase III-theta
Occurring in:
  1. DNA polymerase III subunit theta
The deposited structure of PDB entry 1du2 contains 1 copy of CATH domain 1.20.58.250 (Methane Monooxygenase Hydroxylase; Chain G, domain 1) in DNA polymerase III subunit theta. Showing 1 copy in chain A.
SCOP SCOP annotation
46576
Class: All alpha proteins
Fold: DNA polymerase III theta subunit-like
Superfamily: DNA polymerase III theta subunit-like
Occurring in:
  1. DNA polymerase III subunit theta
The deposited structure of PDB entry 1du2 contains 1 copy of SCOP domain 46576 (DNA polymerase III theta subunit-like) in DNA polymerase III subunit theta. Showing 1 copy in chain A.

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