› 1en1

Solution NMR

STRUCTURE OF THE HIV-1 MINUS STRAND PRIMER BINDING SITE

Released:
DOI: 10.2210/pdb1en1/pdb
PDB entry 1en1 coloured by chain, ensemble of 20 models, front view.
PDB entry 1en1 coloured by chain, ensemble of 20 models, side view.
PDB entry 1en1 coloured by chain, ensemble of 20 models, top view.
Source organism: Synthetic construct
Primary publication:
A mechanism for plus-strand transfer enhancement by the HIV-1 nucleocapsid protein during reverse transcription.
Johnson PE, Turner RB, Wu ZR, Hairston L, Guo J, Levin JG, Summers MF
Biochemistry 39 9084-91 (2000)
PMID: 10924101

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-113752 (preferred)
Entry contents:
1 distinct DNA molecule
Macromolecule:
DNA (5'-D(P*GP*TP*CP*CP*CP*TP*GP*TP*TP*CP*GP*GP*GP*CP*GP*CP*CP*A)-3') Chain: A
Molecule details ›
Chain: A
Length: 18 nucleotides
Theoretical weight: 5.48 KDa
Source organism: Synthetic construct
Expression system: Not provided

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: simulated annealing
Expression system: Not provided

Quick links

Citations

11 review citations

Structural determinants and mechanism of HIV-1 genome packaging.
Lu et al. (2011)
10 more

3 mentions without citation

Three-dimensional modeling of single stranded DNA hairpins for aptamer-based biosensors.
Jeddi et al. (2017)
2 more