Ligands and environments ‹ 1ep4 ‹ Protein Data Bank in Europe (PDBe)

1 bound ligand:

S11 999(A) Environment details ›

Loading 1ep4...

1 modified residue:

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FileManager.getAtomSetCollectionFromFile(https://www.ebi.ac.uk/pdbe/entry-files/download/1ep4.cif)

FileManager opening 1 https://www.ebi.ac.uk/pdbe/entry-files/download/1ep4.cif

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TITLE: Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding.

TITLE: Phenethylthiazolylthiourea (PETT) Non-nucleoside Inhibitors of HIV-1 and HIV-2 Reverse Transcriptases: Structural and Biochemical Analyses

TITLE: Crystallographic Analysis of the Binding Modes of Non-nucleoside Thiazoloisoindolinone Inhibitors to HIV-1 Reverse Transcriptase and Comparison with Modeling Studies

TITLE: Design of MKC-442 (emivirine) Analogues with Improved Activity Against Drug-resistant HIV Mutants

TITLE: Crystal Structures of Reverse Transcriptase in Complex with Carboxanilide Derivatives

TITLE: 3'-azido-3'-deoxythymidine Drug Resistance Mutations in HIV-1 Reverse Transcriptase can Induce Long Range Conformational Changes

TITLE: Continuous and Discontinuous Changes in the Unit Cell of HIV-1 Reverse Transcriptase Crystals on Dehydration

TITLE: Unique Features in the Structure of the Complex Between HIV-1 Reverse Transcriptase and the Bis(heteroaryl)piperazine (BHAP) U-90152 Explain Resistance Mutations for this Non-nucleoside Inhibitor

TITLE: Complexes of HIV-1 Reverse Transcriptase with Inhibitors of the HEPT Series Reveal Conformational Changes Relevant to the Design of Potent Non-nucleoside Inhibitors

TITLE: The Structure of HIV-1 Reverse Transcriptase Complexed with 9-chloro-TIBO: Lessons for Inhibitor Design

TITLE: High Resolution Structures of HIV-1 RT From Four RT-inhibitor Complexes

TITLE: Mechanism of Inhibition of HIV-1 Reverse Transcriptase by Non-nucleoside Inhibitors

TITLE: Crystals of HIV-1 Reverse Transcriptase Diffracting to 2.2 Angstrom Resolution

Setting space group name to HM:P 21 21 21

found biomolecule 1: A,B,C,D,E

unknown CIF bond order: sing

unknown CIF bond order: doub

unknown CIF bond order: sing

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unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

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unknown CIF bond order: doub

unknown CIF bond order: sing

unknown CIF bond order: doub

unknown CIF bond order: sing

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Time for openFile(*1ep4): 2143 ms

reading 7791 atoms

ModelSet: haveSymmetry:false haveUnitcells:true haveFractionalCoord:false

1 model in this collection. Use getProperty "modelInfo" or getProperty "auxiliaryInfo" to inspect them.

Default Van der Waals type for model set to Jmol

7791 atoms created

ModelSet: autobonding; use autobond=false to not generate bonds automatically