› 1eu4

X-ray diffraction
2.5Å resolution

CRYSTAL STRUCTURE OF THE SUPERANTIGEN SPE-H (ZINC BOUND) FROM STREPTOCOCCUS PYOGENES

Released:
DOI: 10.2210/pdb1eu4/pdb
PDB entry 1eu4 coloured by chain, front view.
PDB entry 1eu4 coloured by chain, side view.
PDB entry 1eu4 coloured by chain, top view.
Source organism: Streptococcus pyogenes
Primary publication:
Conservation and variation in superantigen structure and activity highlighted by the three-dimensional structures of two new superantigens from Streptococcus pyogenes.
Arcus VL, Proft T, Sigrell JA, Baker HM, Fraser JD, Baker EN
J Mol Biol 299 157-68 (2000)
PMID: 10860729

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-533380 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Exotoxin type H Chain: A
Molecule details ›
Chain: A
Length: 204 amino acids
Theoretical weight: 23.66 KDa
Source organism: Streptococcus pyogenes
Expression system: Escherichia coli
UniProt:
  • Canonical: P0C0I6 (Residues: 33-236; Coverage: 100%)
Gene name: speH
Sequence domains:
Structure domains:

Ligands and Environments

1 bound ligand:
Ligand ZN 2 x ZN
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: RIGAKU RUH3R
Spacegroup: P21
Unit cell:
a: 36.629Å b: 46.028Å c: 64.47Å
α: 90° β: 91.64° γ: 90°
R-values:
R R work R free
0.205 0.205 0.258
Expression system: Escherichia coli

Quick links

Citations

11 review citations

Toxic shock syndrome and bacterial superantigens: an update.
McCormick et al. (2001)
10 more

2 mentions without citation

Conformational changes in redox pairs of protein structures.
Fan et al. (2009)
1 more