› 1exr

X-ray diffraction
1Å resolution

THE 1.0 ANGSTROM CRYSTAL STRUCTURE OF CA+2 BOUND CALMODULIN

Released:
DOI: 10.2210/pdb1exr/pdb
PDB entry 1exr coloured by chain, front view.
PDB entry 1exr coloured by chain, side view.
PDB entry 1exr coloured by chain, top view.
Source organism: Paramecium tetraurelia
Primary publication:
The 1.0 A crystal structure of Ca(2+)-bound calmodulin: an analysis of disorder and implications for functionally relevant plasticity.
Wilson MA, Brunger AT
J Mol Biol 301 1237-56 (2000)
PMID: 10966818

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-530150 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Calmodulin Chain: A
Molecule details ›
Chain: A
Length: 148 amino acids
Theoretical weight: 16.69 KDa
Source organism: Paramecium tetraurelia
Expression system: Escherichia coli
UniProt:
  • Canonical: P07463 (Residues: 2-149; Coverage: 99%)
Gene names: CAM, GSPATT00015825001
Sequence domains: EF-hand domain pair
Structure domains: EF-hand

Ligands and Environments

1 bound ligand:
Ligand CA 5 x CA
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: SSRL BEAMLINE BL9-2
Spacegroup: P1
Unit cell:
a: 25.015Å b: 29.415Å c: 52.761Å
α: 89.54° β: 86.1° γ: 82.39°
R-values:
R R work R free
0.136 not available 0.163
Expression system: Escherichia coli

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Citations

18 review citations

X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.
Putnam et al. (2007)
17 more

55 mentions without citation

Defining potential roles of Pb(2+) in neurotoxicity from a calciomics approach.
Gorkhali et al. (2016)
54 more