Function and Biology

PVUII ENDONUCLEASE/COGNATE DNA COMPLEX (GLUTARALDEHYDE-CROSSLINKED CRYSTAL) AT PH 7.5 WITH TWO CALCIUM IONS AT EACH ACTIVE SITE

Source organism: Proteus vulgaris
Biochemical function: metal ion binding
Biological process: DNA restriction-modification system
Cellular component: not assigned

EC 3.1.21.4: Type II site-specific deoxyribonuclease

Reaction catalysed:
Endonucleolytic cleavage of DNA to give specific double-stranded fragments with terminal 5'-phosphates
Systematic name:
-
Alternative Name(s):
  • Type II restriction enzyme

GO terms

Sequence family

Pfam Protein family (Pfam)
PF09225
Domain description: Restriction endonuclease PvuII
Occurring in:
  1. Type II restriction enzyme PvuII
The deposited structure of PDB entry 1f0o contains 2 copies of Pfam domain PF09225 (Restriction endonuclease PvuII) in Type II restriction enzyme PvuII. Showing 1 copy in chain C [auth A].

InterPro InterPro annotations
IPR015306
Domain description: Restriction endonuclease, type II, PvuII
Occurring in:
  1. Type II restriction enzyme PvuII
IPR011335
Domain description: Restriction endonuclease type II-like
Occurring in:
  1. Type II restriction enzyme PvuII
IPR038402
Domain description: Restriction endonuclease, type II, PvuII superfamily
Occurring in:
  1. Type II restriction enzyme PvuII

Structure domain

CATH CATH domain
3.40.210.10
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: PvuII Endonuclease; Chain A
Homology: PVUII Endonuclease, subunit A
Occurring in:
  1. Type II restriction enzyme PvuII
The deposited structure of PDB entry 1f0o contains 2 copies of CATH domain 3.40.210.10 (PvuII Endonuclease; Chain A) in Type II restriction enzyme PvuII. Showing 1 copy in chain C [auth A].
SCOP SCOP annotation
52996
Class: Alpha and beta proteins (a/b)
Fold: Restriction endonuclease-like
Superfamily: Restriction endonuclease-like
Occurring in:
  1. Type II restriction enzyme PvuII
The deposited structure of PDB entry 1f0o contains 2 copies of SCOP domain 52996 (Restriction endonuclease PvuII) in Type II restriction enzyme PvuII. Showing 1 copy in chain C [auth A].