Function and Biology Details
Reaction catalysed:
A protein-L-glutamine + a protein-L-lysine = a protein with an N(6)-(gamma-glutamyl)-L-lysine cross-link + NH(3)
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure analysis Details
Assembly composition:
homo dimer (preferred)
Assembly name:
Coagulation factor XIII A chain (preferred)
PDBe Complex ID:
PDB-CPX-523537 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Coagulation factor XIII A chain
Molecule details ›
Chains: A, B
Length: 731 amino acids
Theoretical weight: 83.23 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
Sequence domains:
Length: 731 amino acids
Theoretical weight: 83.23 KDa
Source organism: Homo sapiens
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical:
P00488 (Residues: 2-732; Coverage: 100%)
Sequence domains:
- Transglutaminase family
- Transglutaminase-like superfamily
- Transglutaminase family, C-terminal ig like domain
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
EMBL/DESY, HAMBURG BEAMLINE X11
Spacegroup:
P21
Expression system: Saccharomyces cerevisiae
