EC 2.7.11.1: Non-specific serine/threonine protein kinase
Reaction catalysed:
ATP + a protein = ADP + a phosphoprotein
Systematic name:
ATP:protein phosphotransferase (non-specific)
Alternative Name(s):
- A-kinase
- AP50 kinase
- ATP-protein transphosphorylase
- Beta-IIPKC
- Beta-adrenergic receptor kinase
- CK-2
- CKI
- CKII
- Calcium-dependent protein kinase C
- Calcium/phospholipid-dependent protein kinase
- Casein kinase
- Casein kinase (phosphorylating)
- Casein kinase 2
- Casein kinase I
- Casein kinase II
- Cyclic AMP-dependent protein kinase
- Cyclic AMP-dependent protein kinase A
- Cyclic monophosphate-dependent protein kinase
- Cyclic nucleotide-dependent protein kinase
- Cyclin-dependent kinase
- Cytidine 3',5'-cyclic monophosphate-responsive protein kinase
- Dsk1
- Epsilon PKC
- Glycogen synthase A kinase
- Glycogen synthase a kinase
- Glycogen synthase kinase
- HIPK2
- Hpr kinase
- Hydroxyalkyl-protein kinase
- M phase-specific cdc2 kinase
- MAPK
- Mitogen-activated S6 kinase
- Mitogen-activated protein kinase
- P82 kinase
- PKA
- PKC
- Phosphorylase B kinase kinase
- Phosphorylase b kinase kinase
- Phosphorylase b kinase kinase
- Protein glutamyl kinase
- Protein kinase (phosphorylating)
- Protein kinase A
- Protein kinase CK2
- Protein kinase p58
- Protein phosphokinase
- Protein serine kinase
- Protein serine-threonine kinase
- Protein-aspartyl kinase
- Protein-cysteine kinase
- Protein-serine kinase
- Prp4 protein kinase
- Raf kinase
- Raf-1
- Ribosomal S6 protein kinase
- Ribosomal protein S6 kinase II
- STK32
- Serine kinase
- Serine protein kinase
- Serine(threonine) protein kinase
- Serine-specific protein kinase
- Serine/threonine protein kinase
- T-antigen kinase
- Threonine-specific protein kinase
- Twitchin kinase
- Type-2 casein kinase
- WEE1Hu
- Wee 1-like kinase
- Wee-kinase
- cAMP-dependent protein kinase
- cAMP-dependent protein kinase A
- cGMP-dependent protein kinase
EC 5.2.1.8: Peptidylprolyl isomerase
Reaction catalysed:
Peptidylproline (omega=180) = peptidylproline (omega=0)
Systematic name:
Peptidylproline cis-trans-isomerase
Alternative Name(s):
- Cyclophilin
- PPIase
- Peptide bond isomerase
- Peptidyl-prolyl cis-trans isomerase
- Peptidylprolyl cis-trans isomerase
- Rotamase
GO terms
Biochemical function:
- protein-containing complex binding
- RNA polymerase II CTD heptapeptide repeat P6 isomerase activity
- RNA polymerase II CTD heptapeptide repeat P3 isomerase activity
- activin receptor binding
- I-SMAD binding
- transmembrane transporter binding
- type I transforming growth factor beta receptor binding
- signaling receptor inhibitor activity
- FK506 binding
- macrolide binding
- protein binding
- calcium channel regulator activity
- transforming growth factor beta receptor binding
- peptidyl-prolyl cis-trans isomerase activity
Biological process:
- amyloid fibril formation
- regulation of amyloid precursor protein catabolic process
- supramolecular fiber organization
- heart trabecula formation
- regulation of ryanodine-sensitive calcium-release channel activity
- ventricular cardiac muscle tissue morphogenesis
- protein maturation
- regulation of immune response
- positive regulation of canonical NF-kappaB signal transduction
- T cell activation
- protein refolding
- negative regulation of activin receptor signaling pathway
- regulation of protein localization
- negative regulation of transforming growth factor beta receptor signaling pathway
- regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
- 'de novo' protein folding
- protein folding
- regulation of transcription by RNA polymerase II
- heart morphogenesis
Cellular component:
Sequence families
Protein families (Pfam)
InterPro annotations
Structure domains
CATH domains
1.20.120.150
Class:
Mainly Alpha
Architecture:
Up-down Bundle
Topology:
Four Helix Bundle (Hemerythrin (Met), subunit A)
Homology:
FKBP12-rapamycin binding domain
Occurring in:
SCOP annotations
