› 1g91

Solution NMR

SOLUTION STRUCTURE OF MYELOID PROGENITOR INHIBITORY FACTOR-1 (MPIF-1)

Released:
DOI: 10.2210/pdb1g91/pdb
PDB entry 1g91 coloured by chain, ensemble of 30 models, front view.
PDB entry 1g91 coloured by chain, ensemble of 30 models, side view.
PDB entry 1g91 coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and dynamics of myeloid progenitor inhibitory factor-1 (MPIF-1), a novel monomeric CC chemokine.
Rajarathnam K, Li Y, Rohrer T, Gentz R
J Biol Chem 276 4909-16 (2001)
PMID: 11060285

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-157311 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
CCL23(22-99) Chain: A
Molecule details ›
Chain: A
Length: 77 amino acids
Theoretical weight: 8.87 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P55773 (Residues: 44-120; Coverage: 78%)
  • Best match: P55773-2 (Residues: 64-137)
Gene names: CCL23, MIP3, MPIF1, SCYA23
Sequence domains: Small cytokines (intecrine/chemokine), interleukin-8 like
Structure domains: OB fold (Dihydrolipoamide Acetyltransferase, E2P)

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: distance geometry, simulated annealing, molecular dynamics
Expression system: Escherichia coli

Quick links

Citations

6 review citations

Structure, function, and inhibition of chemokines.
Fernandez et al. (2002)
5 more

5 mentions without citation

The marriage of chemokines and galectins as functional heterodimers.
von Hundelshausen et al. (2021)
4 more