› 1gfc

Solution NMR

SOLUTION STRUCTURE AND LIGAND-BINDING SITE OF THE C-TERMINAL SH3 DOMAIN OF GRB2

Released:
DOI: 10.2210/pdb1gfc/pdb
PDB entry 1gfc coloured by chain, front view.
PDB entry 1gfc coloured by chain, side view.
PDB entry 1gfc coloured by chain, top view.
Source organism: Homo sapiens
Primary publication:
Solution structure and ligand-binding site of the carboxy-terminal SH3 domain of GRB2.
Kohda D, Terasawa H, Ichikawa S, Ogura K, Hatanaka H, Mandiyan V, Ullrich A, Schlessinger J, Inagaki F
Structure 2 1029-40 (1994)
PMID: 7881903

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-158852 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Growth factor receptor-bound protein 2 Chain: A
Molecule details ›
Chain: A
Length: 59 amino acids
Theoretical weight: 6.79 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P62993 (Residues: 159-215; Coverage: 26%)
Gene names: ASH, GRB2
Sequence domains: SH3 domain
Structure domains: SH3 Domains

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Expression system: Not provided

Quick links

Citations

8 review citations

Membrane-associated guanylate kinases regulate adhesion and plasticity at cell junctions.
Funke et al. (2005)
7 more

4 mentions without citation

Diverse recognition of non-PxxP peptide ligands by the SH3 domains from p67(phox), Grb2 and Pex13p.
Kami et al. (2002)
3 more