› 1h7y

Solution NMR

Translationally Controlled Tumor-associated Protein p23fyp from Schizosaccharomyces pombe

Released:
DOI: 10.2210/pdb1h7y/pdb
PDB entry 1h7y coloured by chain, ensemble of 15 models, front view.
PDB entry 1h7y coloured by chain, ensemble of 15 models, side view.
PDB entry 1h7y coloured by chain, ensemble of 15 models, top view.
Source organism: Schizosaccharomyces pombe
Primary publication:
Structure of TCTP reveals unexpected relationship with guanine nucleotide-free chaperones.
Thaw P, Baxter NJ, Hounslow AM, Price C, Waltho JP, Craven CJ
Nat Struct Biol 8 701-4 (2001)
PMID: 11473261

Function and Biology Details

Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-171218 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Translationally-controlled tumor protein homolog Chain: A
Molecule details ›
Chain: A
Length: 168 amino acids
Theoretical weight: 19.07 KDa
Source organism: Schizosaccharomyces pombe
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q10344 (Residues: 1-168; Coverage: 100%)
Gene names: SPAC1F12.02c, p23fy
Sequence domains: Translationally controlled tumour protein
Structure domains: Metal Binding Protein, Guanine Nucleotide Exchange Factor; Chain A

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Chemical shift assignment: 46%
Refinement method: simulated annealing
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

13 review citations

The translationally controlled tumour protein (TCTP).
Bommer et al. (2004)
12 more

1 mention without citation

Comprehensive analysis of Translationally Controlled Tumor Protein (TCTP) provides insights for lineage-specific evolution and functional divergence.
Koo et al. (2020)