Function and Biology

Echovirus 11

Source organism: Echovirus E11
Biochemical function: structural molecule activity
Biological process: not assigned
Cellular component: viral capsid

EC 3.4.22.29: Picornain 2A

Reaction catalysed:
Selective cleavage of Tyr-|-Gly bond in picornavirus polyprotein.
Systematic name:
-
Alternative Name(s):
  • 2A protease
  • 2A proteinase
  • Picornaviral 2A proteinase
  • Picornavirus endopeptidase 2A
  • Poliovirus protease 2A
  • Poliovirus protease 2A-Pro
  • Poliovirus proteinase 2A
  • Protease 2A
  • Proteinase 2A-Pro
  • Rhinovirus protease 2A
  • Y-G proteinase 2A

EC 3.6.1.15: Nucleoside-triphosphate phosphatase

Reaction catalysed:
NTP + H(2)O = NDP + phosphate
Systematic name:
Unspecific diphosphate phosphohydrolase
Alternative Name(s):
  • NTPase
  • Nucleoside 5-triphosphatase
  • Nucleoside triphosphate hydrolase
  • Nucleoside triphosphate phosphohydrolase
  • Nucleoside-5-triphosphate phosphohydrolase
  • Nucleoside-triphosphatase

EC 3.4.22.28: Picornain 3C

Reaction catalysed:
Selective cleavage of Gln-|-Gly bond in the poliovirus polyprotein. In other picornavirus reactions Glu may be substituted for Gln, and Ser or Thr for Gly.
Alternative Name(s):
  • 3C protease
  • 3C proteinase
  • Coxsackievirus 3C proteinase
  • Cysteine proteinase 3C
  • Foot-and-mouth protease 3C
  • Foot-and-mouth-disease virus proteinase 3C
  • Hepatitis A virus 3C proteinase
  • Picornavirus endopeptidase 3C
  • Poliovirus protease 3C
  • Poliovirus proteinase 3C
  • Protease 3C
  • Rhinovirus protease 3C
  • Rhinovirus proteinase 3C
  • Tomato ringspot nepovirus 3C-related protease

EC 2.7.7.48: RNA-directed RNA polymerase

Reaction catalysed:
Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1)
Systematic name:
Nucleoside-triphosphate:RNA nucleotidyltransferase (RNA-directed)
Alternative Name(s):
  • 3D polymerase
  • PB1 proteins
  • PB2 proteins
  • Phage f2 replicase
  • Polymerase L
  • Q-beta replicase
  • RDRP
  • RNA nucleotidyltransferase (RNA-directed)
  • RNA replicase
  • RNA synthetase
  • RNA transcriptase
  • RNA-dependent RNA polymerase
  • RNA-dependent RNA replicase
  • RNA-dependent ribonucleate nucleotidyltransferase
  • Ribonucleic acid replicase
  • Ribonucleic acid-dependent ribonucleate nucleotidyltransferase
  • Ribonucleic acid-dependent ribonucleic acid polymerase
  • Ribonucleic replicase
  • Ribonucleic synthetase
  • Transcriptase

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:

Sequence families

Pfam Protein families (Pfam)
PF00073
Domain description: picornavirus capsid protein
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
The deposited structure of PDB entry 1h8t contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in ECHOVIRUS 11 COAT PROTEIN VP1. Showing 1 copy in chain A.
The deposited structure of PDB entry 1h8t contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in ECHOVIRUS 11 COAT PROTEIN VP2. Showing 1 copy in chain B.
The deposited structure of PDB entry 1h8t contains 1 copy of Pfam domain PF00073 (picornavirus capsid protein) in ECHOVIRUS 11 COAT PROTEIN VP3. Showing 1 copy in chain C.

PF02226
Domain description: Picornavirus coat protein (VP4)
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP4
The deposited structure of PDB entry 1h8t contains 1 copy of Pfam domain PF02226 (Picornavirus coat protein (VP4)) in ECHOVIRUS 11 COAT PROTEIN VP4. Showing 1 copy in chain D.

InterPro InterPro annotations
IPR033703
Domain description: Picornavirus/Calicivirus coat protein
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
IPR001676
Domain description: Picornavirus capsid
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
IPR029053
Domain description: Viral coat protein subunit
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
IPR036988
Domain description: Picornavirus coat protein VP4 superfamily
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP4
IPR003138
Domain description: Picornavirus coat protein VP4
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP4

Structure domains

CATH CATH domains
2.60.120.20
Class: Mainly Beta
Architecture: Sandwich
Topology: Jelly Rolls
Homology: Jelly Rolls
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
The deposited structure of PDB entry 1h8t contains 1 copy of CATH domain 2.60.120.20 (Jelly Rolls) in ECHOVIRUS 11 COAT PROTEIN VP1. Showing 1 copy in chain A.
The deposited structure of PDB entry 1h8t contains 1 copy of CATH domain 2.60.120.20 (Jelly Rolls) in ECHOVIRUS 11 COAT PROTEIN VP2. Showing 1 copy in chain B.
The deposited structure of PDB entry 1h8t contains 1 copy of CATH domain 2.60.120.20 (Jelly Rolls) in ECHOVIRUS 11 COAT PROTEIN VP3. Showing 1 copy in chain C.
4.10.80.10
Class: Few Secondary Structures
Architecture: Irregular
Topology: Rhinovirus 14, subunit 4
Homology: Picornavirus coat protein VP4
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP4
The deposited structure of PDB entry 1h8t contains 1 copy of CATH domain 4.10.80.10 (Rhinovirus 14, subunit 4) in ECHOVIRUS 11 COAT PROTEIN VP4. Showing 1 copy in chain D.
SCOP SCOP annotation
88634
Class: All beta proteins
Fold: Nucleoplasmin-like/VP (viral coat and capsid proteins)
Superfamily: Positive stranded ssRNA viruses
Occurring in:
  1. ECHOVIRUS 11 COAT PROTEIN VP1
  2. ECHOVIRUS 11 COAT PROTEIN VP2
  3. ECHOVIRUS 11 COAT PROTEIN VP3
  4. ECHOVIRUS 11 COAT PROTEIN VP4
The deposited structure of PDB entry 1h8t contains 1 copy of SCOP domain 88634 (Picornaviridae-like VP (VP1, VP2, VP3 and VP4)) in ECHOVIRUS 11 COAT PROTEIN VP1. Showing 1 copy in chain A.
The deposited structure of PDB entry 1h8t contains 1 copy of SCOP domain 88634 (Picornaviridae-like VP (VP1, VP2, VP3 and VP4)) in ECHOVIRUS 11 COAT PROTEIN VP2. Showing 1 copy in chain B.
The deposited structure of PDB entry 1h8t contains 1 copy of SCOP domain 88634 (Picornaviridae-like VP (VP1, VP2, VP3 and VP4)) in ECHOVIRUS 11 COAT PROTEIN VP3. Showing 1 copy in chain C.