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SOLUTION STRUCTURE OF THE EPIDERMAL GROWTH FACTOR-LIKE DOMAIN OF HEREGULIN-ALPHA, A LIGAND FOR P180ERB4

Source organism: Homo sapiens
Biochemical function: signaling receptor binding
Biological process: nervous system development
Cellular component: not assigned

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GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence family

Pfam Protein family (Pfam)
PF00008
Domain description: EGF-like domain
Occurring in:
  1. Neuregulin-1
The deposited structure of PDB entry 1hrf contains 1 copy of Pfam domain PF00008 (EGF-like domain) in Neuregulin-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000742
Domain description: EGF-like domain
Occurring in:
  1. Neuregulin-1
IPR040180
Domain description: Neuregulin
Occurring in:
  1. Neuregulin-1

Structure domain

CATH CATH domain
2.10.25.10
Class: Mainly Beta
Architecture: Ribbon
Topology: Laminin
Homology: Laminin
Occurring in:
  1. Neuregulin-1
The deposited structure of PDB entry 1hrf contains 1 copy of CATH domain 2.10.25.10 (Laminin) in Neuregulin-1. Showing 1 copy in chain A.
SCOP SCOP annotation
57197
Class: Small proteins
Fold: Knottins (small inhibitors, toxins, lectins)
Superfamily: EGF/Laminin
Occurring in:
  1. Neuregulin-1
The deposited structure of PDB entry 1hrf contains 1 copy of SCOP domain 57197 (EGF-type module) in Neuregulin-1. Showing 1 copy in chain A.

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