› 1hz8

Solution NMR

SOLUTION STRUCTURE AND BACKBONE DYNAMICS OF A CONCATEMER OF EGF-HOMOLOGY MODULES OF THE HUMAN LOW DENSITY LIPOPROTEIN RECEPTOR

Released:
DOI: 10.2210/pdb1hz8/pdb
PDB entry 1hz8 coloured by chain, ensemble of 30 models, front view.
PDB entry 1hz8 coloured by chain, ensemble of 30 models, side view.
PDB entry 1hz8 coloured by chain, ensemble of 30 models, top view.
Source organism: Homo sapiens
Primary publication:
NMR structure and backbone dynamics of a concatemer of epidermal growth factor homology modules of the human low-density lipoprotein receptor.
Kurniawan ND, Aliabadizadeh K, Brereton IM, Kroon PA, Smith R
J Mol Biol 311 341-56 (2001)
PMID: 11478865

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-134043 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Low-density lipoprotein receptor Chain: A
Molecule details ›
Chain: A
Length: 82 amino acids
Theoretical weight: 9 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P01130 (Residues: 314-395; Coverage: 10%)
Gene name: LDLR
Structure domains: Laminin

Ligands and Environments

1 bound ligand:
Ligand CA 2 x CA
No modified residues

Experiments and Validation Details

wwPDB Validation report is not available for this NMR entry.
Refinement method: 1. Torsion angles dynamics 2. Restrained molecular dynamics with calcium 3. Energy minimisation
Expression system: Escherichia coli

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Citations

7 review citations

Structure and physiologic function of the low-density lipoprotein receptor.
Jeon et al. (2005)
6 more